The 49ers will travel to Green Bay to face Aaron Rodgers and a Packers team that went 15-1 during the regular season last year. Starting the season on the road against possibly the toughest opponent you'll face all season may not be ideal for San Francisco, but it does give them the opportunity to make a statement with a win.
The 49ers begin their NFC West defense with Alex Smith once again at quarterback. Smith resigned with San Francisco this offseason after a strong 2011 campaign. He will have a few new weapons on offense as Randy Moss and Mario Manningham will make their 49er debuts against the Packers.
Brandon Jacobs could also make his San Francisco debut, but he's listed as questionable to play due to a knee injury. Wide receiver Ted Ginn Jr. is also listed as questionable, although both players traveled to Green Bay with the team.
If the 49ers are going to start the season with a win, they will have to break an eight-game losing streak to the Packers. San Francisco has not beaten Green Bay since 1999.
Game Date/Time: Sunday, Sept. 9; 1:25 p.m. PT
Location: Lambeau Field, Green Bay, Wisconsin
TV Schedule: Fox with announcers Joe Buck and Troy Aikman
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