Just as quickly as word was out that Frank Gore was starting, word quickly changed per @albertbreer to Gore coming off the bench and Kendall Hunter starting. This is an intriguing twist, although it doesn't surprise me given how Jim Harbaugh does sort of what he wants regardless of what he tells the media.
Gore is still expected to get some playing time, but it will be interesting to see how he is mixed in with the rookie Hunter. This has certainly gotten a whole lot more interesting rather quickly.
The 49ers and Eagles both released their inactive lists for the game and there is nothing particularly surprising for the game as seen below:
49ers: QB Scott Tolzien, WR Braylon Edwards, FB Moran Norris, OL Daniel Kilgore, OL Mike Person, NT Ian Williams, DE Demarcus Dobbs
Eagles: CB Curtis Marsh, DE Darryl Tapp, OG Danny Watkins, OT Winston Justice, OG Julian Vandervelde, DE Juqua Parker, CB Brandon Hughes