Lowery injured his ankle in the Jaguars' last game Oct. 7 against the Chicago Bears. The Jaguars had a bye last week.
Wide receiver Laurent Robinson did not pass a concussion test and is also inactive Sunday.
Other Jaguars inactives are linebackers Daryl Smith and Brandon Marshall, defensive end Ryan Davis, offensive lineman Herb Taylor and defensive tackle Jeris Pendleton.
Jaguars defensive end George Selvie will be in uniform for the first time this season, according to Ryan O'Halloran of the Florida Times-Union. Selvie was injured in the preseason and has not played yet in 2012. He practiced Wednesday, Thursday and Friday of this week in preparation for his season debut.
Inactive for the Raiders are quarterback Terrelle Pryor, tight end Richard Gordon, running back Taiwan Jones, defensive lineman Jack Crawford, defensive back Shawntae Spencer, right tackle Khalif Barnes and guard Lucas Nix.
This post originally appeared on SB Nation.