Angel Pagan got the Giants off to an immediate lead, drilling a home run during the game's first at-bat to put San Francisco on top 1-0. Gregor Blanco hit a two-run shot in the third before San Francisco added two runs with small ball in the fifth to go ahead 5-2.
The Giants broke the game open in the top of the seventh with another three runs. Marco Scutaro contributed a double to score a run and Pablo Sandoval hit a two-run shot to add cushion to the lead. He is 2-for-3 with three RBI on the day.
On the mound, Barry Zito only went 2.2 innings and gave up two earned runs off four hits. He also walked four batters. The Reds started Mike Leake, who gave up six hits in 4.1 innings on the mound.
The Giants' eight runs have come off 10 hits.