The 49ers gave up 14 points in the first quarter but were threatening to put a touchdown on the board as the quarter closed. They settled for a field goal attempt that was blocked by defensive lineman Red Bryant and returned for a touchdown by Richard Sherman to give the Seahawks back the momentum and an 18-point lead early in the second quarter.
The Seahawks then added another touchdown with 2:03 remaining in the half on a touchdown pass from Russell Wilson to Anthony McCoy to make it 28-3. David Akers put in a 54-yard field goal near the close of the half to finish the first half scoring.
The Niners' defense looks tired and after playing an NFL-record number of snaps last week against the New England Patriots, and the Seahawks have taken advantage by jumping out to an early lead.
49ers quarterback Colin Kaepernick continues to struggle with only 85 yards on 8-for-19 passing. Wilson has 98 yards on 8-for-9 passing, two touchdowns and one interception.
49ers tight end Vernon Davis was knocked out of the game on a vicious hit by Kam Chancellor and will not return after suffering a concussion.