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49ers vs. Seahawks betting lines & odds

The 49ers are seven-point favorites over the Seahawks on Thursday night.

Otto Greule Jr - Getty Images

The San Francisco 49ers are sitting as seven-point favorites as they host the Seattle Seahawks on Thursday night.

The 49ers and the Seahawks are both 4-2 and sitting tied with the Arizona Cardinals at the top of the NFC West. Both teams are coming from wildly different Week 6 results. The Seahawks orchestrated a late comeback to topple the New England Patriots, 24-23. The 49ers are coming off of a 26-3 loss against the New York Giants.

The over/under on the game is sitting at 37.5 points. Both teams don't score a lot of points and rely on their defenses stopping their opponents. Combined, the two teams average a total 43.6 points, but each squad holds opponents to less than 16 points a game.

The 49ers have won three straight contests against the Seahawks. The last time they lost to the Seahawks was Week 1 of 2010, a 31-6 loss in Seattle. Week 7 is the first of two meetings between the two teams.