The Raiders didn't suffer any major injuries in the rout. Many Oakland players were unable to play in the game - Darrius Heyward-Bey was inactive with a concussion, Khalif Barnes sat out the game at right tackle with a groin injury, with Willie Smith stepping into an offensive line that allowed three sacks for 21 yards, and cornerback Shawntae Spencer's foot injury forced Joselio Hanson into duty, where he recorded five tackles. Andre Carter was a late scratch, as the new roster addition at defensive end still hasn't recovered from a torn quad last season. The Raiders had hoped he would play this week, but he will have two additional weeks to heal accustom himself to his new team as Oakland heads into a bye week.
Denver wasn't lucky enough to stay off the injury report, as their center, J.D. Walton, hurt his ankle and had to leave the game.