Just about an hour out from gametime and the inactive players have been announced. For the 49ers, Dashon Goldson, Kyle Williams, Ian Williams, Daniel Kilgore, Mike Person, Scott Tolzien and Demarcus Dobbs will not be suiting up. Of note in that list is Goldson, the team's starting free safety. A nagging injury will keep him out and in his place will be Madieu Williams, making his first regular season start as a San Francisco 49er. The team most likely intended for Williams to be the starter when they signed him in the offseason anyway, but Goldson returned at a good price and that pushed him down the depth chart.
For the Seahawks: Josh Portis, Kris Durham, Sidney Rice, David Hawthorne, Robert Gallery, Jarriel King and Al Woods will be inactive. Three names pop out there: Rice, Hawthorne and Gallery. Rice was the team's big free agent signing and he's out with an injury, while Ben Obomanu will step up for his pace on the depth chart. Gallery is an above-average guard who will be replaced by a shifting John Carpenter, while Hawthorne will be replaced by rookie K.J. Wright.
That's a couple of significant players missing for Seattle, while Williams remains an unknown commodity for San Francisco, but he did play well in the preseason, for whatever that is worth.