Alex Gonzalez and Brooks Conrad added two hits and an RBI each for the Braves, who have won five of seven games and maintained their division lead over Philadelphia by two games.
Omar Infante chipped in with a solo home run and Melky Cabrera collected three hits and drove in an insurance run in the eighth as part of a 12-hit attack.
Derek Lowe (11-9) pitched 5 1/3 innings and was reached for five hits and two runs before being pulled by manager Bobby Cox due to cramping in his left hamstring. Takashi Saito worked the ninth to record his first save since April 26, 2009 while with Boston.
"I think coming into the series...everyone looked at the rotations -- you expect it to be good pitching games all four games. It pretty much turned out to be that way," said Lowe, who along with Jair Jurrjens, Tommy Hanson and Tim Hudson held the Giants to five runs over 26 1/3 innings in the series.
Travis Ishikawa homered as part of a 2-for-4 showing for the Giants, who wrapped up a 2-4 road trip by dropping three of four in the series. Jonathan Sanchez (8-7) lasted just four frames in the start, allowing four runs on five hits and three walks.
San Francisco got things going in the second inning when Pat Burrell led off with a single and scored whenJuan Uribe hit a double to left-center.
The Braves came back with three in the bottom half to move in front for good. Conrad opened with a two-bagger and scored on Ross' one-out home run to left.
"It's baseball, you know, you can't expect to win all the games. We came here to win all the games, we just have to go back home and start winning again," said Sanchez. "They are a pretty good team. Ross was the pitch that killed me. That was bad pitching today."
A pair of walks and a Cabrera single loaded the bases and Gonzalez made it a 3-1 game with a sacrifice fly. Infante hit a two-out homer in the fourth to push the advantage to three.
Todd Wellemeyer took over for Sanchez in the fifth and loaded the bases right out of the shoot. Conrad came through with a base hit to score Gonzalez before Santiago Casilla entered and limited the damage.
Andres Torres doubled leading off the sixth and was allowed to score when Troy Glaus fumbled a grounder at first off the bat of Pablo Sandoval. Peter Moylan took over for Lowe with one out and got out of the inning without further incident, but he served up a leadoff homer to Ishikawa an inning later to make it a 5-3 game.
Jonny Venters was summoned after Moylan put another runner on and eventually induced an inning-ending double play from Torres. Venters and Kyle Farnsworth combined to pitch a flawless eighth.
Cabrera singled home Ross in the home half to increase the lead to 6-3.
Lowe is considered day-to-day and improved his record at Turner Field to 8-3 in 12 starts this season. The right-hander came in 1-4 in his last seven starts...Sanchez threw six shutout innings and scattered three hits with nine strikeouts his last time out in a 10-0 destruction of Colorado...The Giants went 2-for-33 with runners in scoring position during the series. They were 1- for-10 Sunday...Chipper Jones and Billy Wagner were both given the day off from their respective roles in Atlanta...The Braves are 40-2 this year when scoring five or more runs and 15-1 in day games at home...Highly-touted left- hander Mike Minor will make his major league debut Monday for the Braves in Houston to start a three-game series...San Francisco returns home for four games with the Cubsstarting Monday with Madison Bumgarner toeing the rubber...Infante has an 11-game hitting streak.