San Francisco, CA (Sports Network) - Juan Uribe blasted a solo home run and Buster Posey added three hits with an RBI to help San Francisco beat Boston, 5-4, in the opener of a three-game interleague series at AT&T Park.
San Francisco increased its lead to 5-3 on a Freddy Sanchez sacrifice fly in the bottom of the eighth.
The Red Sox refused to go quietly in the ninth.
Kevin Youkilis ripped a two-out triple off Giants closer Brian Wilson and scored on a single by Victor Martinez. Adrian Beltre kept the game alive with a single and Bill Hall drew a walk, but Boston wound up leaving the bases loaded for the third time in the last four innings after Darnell McDonald grounded out to end the contest.
Wilson earned his 21st save of the season.
A three-run homer by Youkilis in the first inning was among three hits given up by Giants starter Jonathan Sanchez (6-5). The left-hander struck out six and walked four over 5 1/3 innings.
Tim Wakefield (2-6) gave up four runs -- three earned -- on 11 hits in seven innings to get the loss, the third in the last four games for Boston.
The Red Sox jumped out to a 3-0 lead in the first inning. Sanchez gave up a single to Marco Scutaro to begin the game and walked Daniel Nava. After Dustin Pedroia struck out, Youkilis sent the eighth pitch of his at-bat over the left-field wall.
San Francisco answered with three runs in the second. Pablo Sandoval stroked a one-out single, advanced to second on a wild pitch and scored on a base hit by Posey.
Aaron Rowand walked and Eli Whiteside reached on a ground ball that was deflected by Wakefield to load the bases. Sanchez then dropped down a bunt to plate Rowand, with the tying run scoring on Wakefield's throwing error.
Uribe's blast with one out in the third gave the Giants a 4-3 lead.
Pedroia left the game in the top of the third inning after fouling a ball off his left foot...The Giants have won three of their last five games...Boston finished 2-for-10 with runners in scoring position and left 13 men on base.