Smith reportedly tore his triceps against the New England Patriots on Dec. 16 and hasn't practiced since. His streak of 185 consecutive starts ended last week after he missed Week 16's game against the Seattle Seahawks. He was listed doubtful on the 49ers injury report, but didn't practice all week. If he is on the sideline, he will be hanging out with wide receiver Mario Manningham who was declared out with a knee injury.
The following 49ers are listed as probable for the game: linebackers Tavaraes Gooden (illness, rib), Aldon Smith (shoulder), NaVorro Bowman (wrist, shoulder), cornerbacks Tarell Brown (shoulder, knee) and Carlos Rogers (knee, toe), running back Frank Gore (knee), offensive lineman Mike Iupati (shoulder) and Jonathan Goodwin (illness), safeties Trenton Robinson (finger) and Donte Whitner (knee) and punter Andy Lee (illness).
The Cardinals will be without the services of wide receiver Early Doucet, who has been ruled out because of a concussion. Wide receiver Laron Byrd is also listed as doubtful with a knee injury and did not practice all week.
The following Cardinals are listed as questionable: offensive lineman Mike Gibson (calf) and Nate Potter (ankle), running back Anthony Sherman (knee) and defensive end Ronald Talley (ankle). The following players are probable for the Cardinals: safeties Adrian Wilson (illness), Rashad Johnson (hamstring), James Sander (calf), Kerry Rhodes (illness), defensive tackle Dan Williams (hamstring) and cornerback Gregory Toler (hamstring).