San Francisco 49ers wide receiver Mario Manningham continues to be limited by a shoulder injury and his status for Sunday's game against New England is in doubt.

Manningham, who missed last week's game against Miami due to the injury, was a limited participant in practice on Thursday. His 41 catches this season are second on the team, trailing just Michael Crabtree's 66. After playing somewhat of a limited role early in the season, Manningham has increased his production lately catching five passes in each of his last two games.

With Manningham's status in doubt, it could open the door for rookie wide receiver A.J. Jenkins. Jenkins, who San Francisco selected with the No. 30 pick in the 2012 NFL Draft, was active for the first time this season last week. While he did not catch a pass against the Dolphins, Jenkins could begin to grow into a larger role in the offense if Manningham continues to miss time.