Struggling David Akers says he feels horrible after missed kick

Akers's rough season continues after missing a potential game-winning field goal in overtime against the St. Louis Rams.

49ers vs. Rams injury report: Mario Manningham's status uncertain

The 49ers have to deal with an injury to wide receiver Mario Manningham.

49ers vs. Rams injury report: Demarcus Dobbs out for Sunday, Darcel McBath questionable for 49ers

The San Francisco 49ers enter Sunday's contest against the St. Louis Rams at almost full strength. The only San Francisco player officially out for Sunday is tight end Demarcus Dobbs.

49ers vs. Rams: Can Colin Kaepernick live up to the moment?

Following Jim Harbaugh's decision, we discuss whether or not San Francisco 49ers quarterback Colin Kaepernick can seize the moment in Week 13.

49ers vs Rams: 49ers' defense lucky to escape with a tie

The 49ers and Rams played to a 24-24 tie on Sunday. The offense, led for most of the game by backup quarterback Colin Kaepernick did their part. The defense, on the other hand, let a previously listless Rams offense steal the show in a game neither team deserved to win.

49ers vs. Rams injury report

Quarterback Alex Smith suffered a concussion during the 49ers 24-24 tie with the St. Louis Rams, but may still be able to play against the Bears on Monday night.

49ers vs. Rams: SF players, coaches not sure how to feel after tie

The hard-fought division game vs. the Rams left San Francisco's players and coaches on both sides with an empty feeling following the NFL's first tie since 2008.

49ers vs. Rams: Is there a quarterback controversy after pseudo-comeback?

The San Francisco 49ers have two capable quarterbacks in Alex Smith and Colin Kaepernick

49ers QB Alex Smith threw touchdown pass with blurred vision

Alex Smith suffered a concussion versus the St. Louis Rams on Sunday.

Alex Smith injury: 49ers quarterback improving after concussion

Smith will see a neurologist this afternoon to help determine if he'll be cleared to play next Monday against the Bears.

49ers vs. Rams final score: St. Louis, San Francisco play to 24-24 tie

The St. Louis Rams and San Francisco 49ers were unable to score in overtime, as the two NFC West teams played to a 24-24 tie.

Rams vs. 49ers score update: San Francisco still down 17-7 entering fourth quarter

The San Francisco 49ers were unable to make up any ground on the Rams in the third quarter, as they trail St. Louis 17-7 going into the final quarter of play.

Backup quarterback Colin Kaepernick was largely ineffective after replacing Alex Smith, who suffered a concussion in the second quarter and will not return. Kaepernick is 2/7 for 14 yards passing and has an additional 14 yards rushing.

The Rams ate up a large chunk of the third quarter with a 16 play, 60 yard drive that consumed over eight minutes of playing time. The possession ended with a 27 yard field goal by kicker by Greg Zuerlein.

San Francisco was only able to muster one offensive series for the quarter. Wide receiver Michael Crabtree remains the 49ers' top threat with 59 yards and a touchdown reception. San Francisco has been outgained in total yards 279 to 183 on the day.

Rams vs. 49ers update: Alex Smith leaves game with concussion, won't return

San Francisco 49ers starting quarterback Alex Smith left Sunday's game against the St. Louis Rams after suffering a concussion and will not return.

The injury occurred in the second quarter following a helmet-to-helmet hit by St. Louis linebacker Jo-Lonn Dunbar. The San Francisco 49ers' official Twitter feed confirmed that Smith will not play for the remainder of the afternoon.

Alex Smith is out for the remainder of the game with a concussion.

— San Francisco 49ers (@49ers) November 11, 2012

Smith was 7/8 for 72 yards and a touchdown at the time of the injury. He was replaced by second-year player Colin Kaepernick, who is 1/4 for three yards with an additional 14 rushing yards in his absence.

On the season, Smith has thrown for 1,659 yards, 12 touchdowns and five interceptions. The 49ers entered the day with a 6-2 record but trail the St. Louis Rams 14-7 after the first half of play.

Rams vs. 49ers score update: Alex Smith concussed, 49ers trail 14-7 at halftime

The San Francisco 49ers trail the St. Louis Rams 14-7 at halftime, and starting quarterback Alex Smith will not return to the game after suffering a concussion.

The 49ers, who were down 14-0 going into the second quarter, were able to get on the board after a 12 play, 78 yard drive that took up over eight minutes of playing time. Michael Crabtree completed the possession with a 14 yard touchdown catch from Smith.

But on San Francisco's next drive, Colin Kaepernick replaced Smith, who was injured on a helmet-to-helmet collision.

Alex Smith is out for the remainder of the game with a concussion.

— San Francisco 49ers (@49ers) November 11, 2012

Smith was 7/8 for 72 yards and a touchdown at the time of his exit. Kaepernick is 1/4 for three yards as his replacement.

Frank Gore, meanwhile, leads the 49ers with 51 yards on 11 carries. Crabtree is the team's top receiver with 59 yards and a touchdown grab.

Rams vs. 49ers score update: San Francisco trials St. Louis 14-0 after first quarter

Following the first quarter of play, the San Francisco 49ers find themselves in a surprising 14-0 hole at home against the St. Louis Rams.

The Rams have scored on both of their possessions against San Francisco's usually stout defense. The 49ers went three-and-out in their opening drive, which St. Louis followed up with a six play, 66 yard drive culminating in a 36 yard touchdown pass from Sam Bradford to wide receiver Brian Quick.

San Francisco advanced into St. Louis territory on their next possession but once again was forced to punt. The Rams responded by marching 93 yards in seven plays and scoring again on a seven yard touchdown run by Steven Jackson.

Bradford is a perfect 4-of-4 for 73 yards and a touchdown, while Alex Smith is 3-of-4 for 22 yards. No receiver has more than one reception for the 49ers, who have been outgained by San Francisco in total offense, 149 to 53 yards.

NFL inactives, Rams vs. 49ers: Danny Amendola will play against San Francisco

Wide receiver Danny Amendola will suit up Sunday afternoon as the St. Louis Rams and San Francisco 49ers battle from Candlestick Park.

49ers vs. Rams preview: Can the St. Louis defense slow down the 49ers?

Can the 49ers' offense put up the necessary points against a passable and improving Rams defense? If week 8 was any indication, the answer is yes.

49ers vs. Rams injury report: Frank Gore, Patrick Willis both probable

The 49ers have been fortunate to avoid the injury bug this season. They'll be at full strength yet again in Week 10.

Patrick Willis, 49ers' defense must take away big plays by St. Louis

The 3-5 St. Louis Rams may not seem like they'll be any trouble for the Niners' stout defense, but in the NFL, things aren't always what they seem.

49ers vs. Rams injury report: San Francisco as healthy as it can be

The San Francisco 49ers had all of their injured players fully practice on Thursday in preparation for Sunday's game against the St. Louis Rams.

49ers vs. Rams betting lines & odds: San Francisco favored by double digits

The San Francisco 49ers are double-digit favorites over the St. Louis Rams.

Following another alleged incident, 49ers' Aldon Smith says he's growing up

Aldon Smith has had an eventful career off the field in just two short years in the NFL, and given his latest near-incident, he's learning to keep himself out of trouble.

49ers vs. Rams injury report: Key players all expected to practice Thursday

Coming off a bye, the 49ers appear to be fully healthy heading into Sunday's matchup with the St. Louis Rams. Several players have nagging injuries, but all are expected to practice on Thursday.

49ers vs. Rams preview: How well do 49ers know Sam Bradford?

Sam Bradford did not play In the two 2011 match-ups between the 49ers and Rams. Does this give the Rams any advantage?

NFC playoff picture: 49ers in control of division after Week 9

The 49ers enjoy a lead in the division race, but still has work to do if it wants to earn a bye.

San Francisco 49ers vs. St. Louis Rams game preview: All you need to know for Week 10

An in-depth preview of the matchup between the San Francisco 49ers and the St. Louis Rams in Week 10 of the 2012 NFL season.