49ers vs Giants: Turnovers, short fields make for blowout

Alex Smith's interceptions, short fields allow Giants to dominate an otherwise evenly matched game.

49ers' Alex Boone primary tackle backup, despite starting at RG

Left tackle Joe Staley received his second concussion since December on Sunday. Stepping into his spot was Alex Boone, normally the right guard.

49ers vs. Giants: San Francisco gave up on run game too early

The 49ers threw the ball over double the amount of times than ran the ball Sunday afternoon which isn't usually a recipe for success for this team.

49ers vs. Giants final score: New York trounces San Francisco, 26-3

The San Francisco 49ers fell to the New York Giants on Sunday afternoon, losing 26-3.

49ers vs. Giants: Missed field goals cap first half with New York up 10-3

The San Francisco 49ers and New York Giants each had chances to put points on the board late in the first half, but neither converted so the Giants head into the half with a 10-3 lead after a strong second quarter.

The 49ers led 3-0 after the first quarter, but the Giants grabbed the lad back on a six-yard touchdown pass to Victor Cruz. On their next drive, the Giants drove down the field again and this time capped it with a 34-yard Lawrence Tynes to extend their lead to 10-3.

It looked like New York would add to that lead on their final drive of the half, but Tynes had a field goal blocked. That should have ended the half, but a 36-yard pass put San Francisco in field goal range and set up a last second attempt by David Akers. Unfortunately for the Niners, he missed his second field goal of the day.

Both the Giants and 49ers have had their struggles and successes on both sides of the ball. At the half, they are pretty even with New York racking up 199 yards of offense and the 49ers 173 yards.

49ers vs. Giants: David Akers field goal gives San Francisco 3-0 lead

The San Francisco 49ers came out firing in Sunday's much anticipated clash with the New York Giants, but despite their early dominance they only have a 3-0 lead to show for it after the first quarter.

The 49ers returned to start the game and went 50 yards on 12 plays to set up David Akers for a 43-yard field goal. That drive went for naught, though, because Akers' field goal attempted missed wide.

After a quick three-and-out, San Francisco got the ball back and put together another solid drive. Once again they had 12 plays on the drive, this time setting Akers up for a 42-yard field goal attempt, which he nailed to give the 49ers a 3-0 lead.

Alex Smith has been solid in the first quarter, completing eight of 13 passes for 68 yards. The 49ers have done their real damage on the ground, picking up 52 yards on just nine carries. Still, they will not be happy that despite completely dominating the Giants they lead by just three points.

NFL inactives, Week 6: Giants vs. 49ers

Brandon Jacobs is inactive for the San Francisco 49ers -- once again.

NFL TV coverage maps: 49ers, Raiders headline Bay Area schedule

Previewing all of Sunday's NFL action for Week 6.

49ers vs Giants: Battle in the trenches key to victory

Taking a closer look at the offensive lines for the 49ers and Giants in their rematch of the NFC Championship Game.

49ers vs. Giants injury report: Niners look pretty healthy for Sunday

The Niners should have close to a full squad on Sunday as they take on the New York Giants.

Jim Harbaugh calls Giants' comments on Justin Smith 'outrageous, irrational'

San Francisco head coach Jim Harbaugh went out of his way Friday to respond to Kevin Gilbride's criticism of 49ers DE Justin Smith.

49ers vs. Giants: Special teams play to dictate momentum in rematch

The San Francisco 49ers will face the New York Giants in a battle for NFC supremacy. The key to a successful game plan for the 49ers will be their special teams play and eliminating the mistakes that cost them a shot at the Super Bowl less than a year ago.

49ers vs. Giants betting lines and odds

The 49ers came in as favorites, and the line has only gotten larger as confidence grows in the team's ability to knock off the defending Super Bowl champion Giants.

49ers vs. Giants injury report: San Francisco healthy heading into Week 6

The 49ers are as close to completely healthy as it gets heading into their game against the Giants.

Brandon Jacobs injury: 49ers RB says he's healthy, is growing frustrated

49ers running back Brandon Jacobs is getting a bit irked that he's hasn't been getting any playing time, claiming that he's been healthy enough to play for the last two weeks.

49ers vs. Giants injury report: Alex Smith, Brandon Jacobs back at practice on Wednesday

The San Francisco 49ers emerged from their Week 5 win against the Buffalo Bills without any significant injuries and look to be fully healthy heading into Sunday's game against the New York Giants.

Alex Smith injury update: Jim Harbaugh says quarterback's finger is 'fine'

San Francisco 49ers coach Jim Harbaugh said that quarterback Alex Smith's finger was fine after watching Smith throw the ball on Tuesday.

49ers vs. Giants preview: Offense must keep contributing

The 49ers defense and special teams haven't had the gaudy statistics they put up in 2011 thus-far. The offense however has taken a step forward. They need to keep it up in order to win certain games.