Current reports indicate that neither will miss a significant amount of time during the regular season, but Jacobs' injury appears to be more serious than James'. Jacobs hurt his left knee after being tackled by Texans cornerback Kareem Jackson. He was later helped off the field by coach Jim Harbaugh and the team's trainer. Harbaugh told the media that Jacob's injury is not season-ending.
After Saturday night's game, LaMichael James tweeted out that he expects to be on the field and practicing on Monday:
I will be 100% at practice Monday In full force believe that go 9ers thanks for all the support I love you guys!— LaMichael James (@LaMichaelJames) August 19, 2012
Niners Nation writer David Fucillo speculates that the 49ers might add a running back in response to Jacob's injury:
At the same time, as I mentioned after LaMichael James went down with an apparent ankle injury, I wouldn't be surprised to see the 49ers add a running back this week. Whether it be Ryan Grant or anybody else (Kory Sheets anybody?!?!), an extra body would help at least allow the 49ers to roll out some more bodies to keep Frank Gore and Kendall Hunter as fresh as possible. (Via: Niners Nation)
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